Assessment of The Effect of Niacin-Hedra helix Extract Combined Treatment on Some Biochemical Parameters in Induced-Asthma Male Mice

The point of the present work was intended to think about impacts Niacin, Hedera helix  on asthma. Related parameters after enlistment asthma for 28 days and in Balb/c mice, notwithstanding research a plausibility accomplishing joined advantage niacin treatment on cytokines, total protein histological examination lung. white differential blood count BAL (Eosinophil infiltration) is Asthma marker.  activity level GSH tissue lung mice recorded significant increases (p ≤ 0.05) that significantly decreased group compared control group.  which treated by combination increased 39.9% group. thiol T-thiol all groups niacin, 60.8%, 60.6%, 68.3%; respectively, while decreased. There were decreases SOD –Hedera as group, recording 121.3%, 54.7% 130.7% when with results showed data difference between 0.001, 0.602 0.001 huge increment TNF-α while, other there diminished contrasted Hedera, niacin-Hedera blend 0.999, 0.920 0.812; respectively.